CBFB protein (Homo sapiens) - STRING interaction network

CBFB protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	CBFB	core-binding factor, beta subunit; CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. CBFB enhances DNA binding by RUNX1 (187 aa)
		(Homo sapiens)
Predicted Functional Partners:
	RUNX1	runt-related transcription factor 1; CBF binds to the core site, 5'-PYGPYGGT-3', of a number of [...] (480 aa)	•	•	•	0.999
	RUNX3	runt-related transcription factor 3; CBF binds to the core site, 5'-PYGPYGGT-3', of a number of [...] (429 aa)	•	•	•	0.997
	RUNX2	runt-related transcription factor 2; Transcription factor involved in osteoblastic differentiat [...] (589 aa)	•		•	0.997
	MYH11	myosin, heavy chain 11, smooth muscle; Muscle contraction (1979 aa)			•	0.956
	IGHA1	immunoglobulin heavy constant alpha 1; Ig alpha is the major immunoglobulin class in body secre [...] (353 aa)		•	•	0.928
	SMAD4	SMAD family member 4; Common mediator of signal transduction by TGF-beta (transforming growth f [...] (552 aa)		•	•	0.899
	CEBPZ	CCAAT/enhancer binding protein (C/EBP), zeta; Stimulates transcription from the HSP70 promoter (1054 aa)	•		•	0.857
	ETV6	ets variant 6; Transcriptional repressor; binds to the DNA sequence 5'- CCGGAAGT-3' (452 aa)			•	0.856
	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related); Transcription regul [...] (604 aa)			•	0.847
	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3; Functions as a transcrip [...] (653 aa)			•	0.828

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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