LAMP2 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.

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lysosomal-associated membrane protein 2; Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens (411 aa)
(Homo sapiens)
Predicted Functional Partners:
CD63 molecule; This antigen is associated with early stages of melanoma tumor progression. May [...] (238 aa)
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae); Required for the assembly of the V0 complex o [...] (101 aa)
selectin P (granule membrane protein 140kDa, antigen CD62); Ca(2+)-dependent receptor for myelo [...] (830 aa)
FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae); The PI(3,5)P2 regulator [...] (907 aa)
epidermal growth factor receptor pathway substrate 8; Upon binding to EGF receptor enhances EGF [...] (822 aa)
scavenger receptor class B, member 2; May act as a lysosomal receptor (478 aa)
glucosidase, alpha; acid; Essential for the degradation of glygogen to glucose in lysosomes (952 aa)
microtubule-associated protein 1 light chain 3 alpha; Probably involved in formation of autopha [...] (125 aa)
Vac14 homolog (S. cerevisiae); The PI(3,5)P2 regulatory complex regulates both the synthesis an [...] (782 aa)
ATP-binding cassette, sub-family B (MDR/TAP), member 9; May function as a peptide transporter (766 aa)
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
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