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  LAMP2 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
LAMP2
lysosomal-associated membrane protein 2; Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens (411 aa)
(Homo sapiens)
Predicted Functional Partners:
CD63
CD63 molecule; This antigen is associated with early stages of melanoma tumor progression. May [...] (238 aa)
      0.992
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae); Required for the assembly of the V0 complex o [...] (101 aa)
       0.946
SELP
selectin P (granule membrane protein 140kDa, antigen CD62); Ca(2+)-dependent receptor for myelo [...] (830 aa)
      0.918
FIG4
FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae); The PI(3,5)P2 regulator [...] (907 aa)
       0.898
EPS8
epidermal growth factor receptor pathway substrate 8; Upon binding to EGF receptor enhances EGF [...] (822 aa)
       0.868
SCARB2
scavenger receptor class B, member 2; May act as a lysosomal receptor (478 aa)
       0.837
GAA
glucosidase, alpha; acid; Essential for the degradation of glygogen to glucose in lysosomes (952 aa)
       0.836
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha; Probably involved in formation of autopha [...] (125 aa)
       0.822
VAC14
Vac14 homolog (S. cerevisiae); The PI(3,5)P2 regulatory complex regulates both the synthesis an [...] (782 aa)
       0.818
ABCB9
ATP-binding cassette, sub-family B (MDR/TAP), member 9; May function as a peptide transporter (766 aa)
       0.803
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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