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  CXCL1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO- alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity (107 aa)
(Homo sapiens)
Predicted Functional Partners:
CXCR2
chemokine (C-X-C motif) receptor 2; Receptor for interleukin-8 which is a powerful neutrophil c [...] (360 aa)
     0.999
CXCR1
chemokine (C-X-C motif) receptor 1; Receptor to interleukin-8, which is a powerful neutrophils [...] (350 aa)
     0.996
CXCL2
chemokine (C-X-C motif) ligand 2; Produced by activated monocytes and neutrophils and expressed [...] (107 aa)
    0.989
CXCL3
chemokine (C-X-C motif) ligand 3; Ligand for CXCR2 (By similarity). Has chemotactic activity fo [...] (107 aa)
    0.986
CCL5
chemokine (C-C motif) ligand 5; Chemoattractant for blood monocytes, memory T-helper cells and [...] (91 aa)
      0.984
CCL20
chemokine (C-C motif) ligand 20; Chemotactic factor that attracts lymphocytes and, slightly, ne [...] (96 aa)
     0.984
CCR1
chemokine (C-C motif) receptor 1; Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP- [...] (355 aa)
      0.971
CXCL11
chemokine (C-X-C motif) ligand 11; Chemotactic for interleukin-activated T-cells but not unstim [...] (94 aa)
      0.969
CCR5
chemokine (C-C motif) receptor 5; Receptor for a number of inflammatory CC-chemokines including [...] (352 aa)
      0.968
IL1B
interleukin 1, beta; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation [...] (269 aa)
      0.966
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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