POU2F2 protein (Homo sapiens) - STRING interaction network

POU2F2 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	POU2F2	POU class 2 homeobox 2; Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter (463 aa)
		(Homo sapiens)
Predicted Functional Partners:
	POU2AF1	POU class 2 associating factor 1; Transcriptional coactivator that specifically associates with [...] (256 aa)	•		•	0.989
	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; NF-kappa-B is a pleiotrop [...] (969 aa)		•	•	0.984
	TBP	TATA box binding protein; General transcription factor that functions at the core of the DNA-bi [...] (339 aa)	•		•	0.960
	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); Receptor for glucoco [...] (778 aa)	•		•	0.939
	SLC26A3	solute carrier family 26, member 3; Chloride/bicarbonate exchanger. Involved in absorbtion of i [...] (764 aa)			•	0.920
	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian); NF-kappa-B is a pleiotropic trans [...] (551 aa)		•	•	0.914
	IVL	involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia [...] (585 aa)			•	0.891
	MUCL1	mucin-like 1; May play a role as marker for the diagnosis of metastatic breast cancer (90 aa)			•	0.891
	SYN1	synapsin I; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, an [...] (705 aa)			•	0.853
	NOS1	nitric oxide synthase 1 (neuronal); Produces nitric oxide (NO) which is a messenger molecule wi [...] (1434 aa)			•	0.834

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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