FANCA protein (Homo sapiens) - STRING interaction network

FANCA protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	FANCA	Fanconi anemia, complementation group A; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability (1455 aa)
		(Homo sapiens)
Predicted Functional Partners:
	FANCG	Fanconi anemia, complementation group G; DNA repair protein that may operate in a postreplicati [...] (622 aa)	•	•	•	0.999
	FANCC	Fanconi anemia, complementation group C; DNA repair protein that may operate in a postreplicati [...] (558 aa)	•	•	•	0.999
	FANCF	Fanconi anemia, complementation group F; DNA repair protein that may operate in a postreplicati [...] (374 aa)	•	•	•	0.999
	FANCE	Fanconi anemia, complementation group E; Required for the nuclear accumulation of FANCC and pro [...] (536 aa)	•	•	•	0.999
	FANCL	Fanconi anemia, complementation group L; Ubiquitin ligase protein that mediates ubiquitination [...] (380 aa)	•	•	•	0.999
	FANCM	Fanconi anemia, complementation group M; ATPase required for FANCD2 ubiquitination, a key react [...] (2048 aa)	•	•	•	0.999
	FANCB	Fanconi anemia, complementation group B; DNA repair protein required for FANCD2 ubiquitination (859 aa)	•	•	•	0.998
	C17orf70	Fanconi anemia-associated protein of 100 kDa ; Play a role in Fanconi anemia-associated DNA dam [...] (730 aa)	•	•	•	0.998
	BRCA1	breast cancer 1, early onset; The BRCA1-BARD1 heterodimer coordinates a diverse range of cellul [...] (1863 aa)	•	•	•	0.997
	FANCD2	Fanconi anemia, complementation group D2; Required for maintenance of chromosomal stability. Pr [...] (1471 aa)		•	•	0.997

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes

Server load: medium (43%)

Permalink