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  COLQ protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase; Anchors the catalytic subunits of asymmetric AChE to the synaptic basal lamina (455 aa)
(Homo sapiens)
Predicted Functional Partners:
ACHE
acetylcholinesterase (Yt blood group); Terminates signal transduction at the neuromuscular junc [...] (617 aa)
      0.994
BCHE
butyrylcholinesterase (602 aa)
      0.977
MUSK
muscle, skeletal, receptor tyrosine kinase; Receptor tyrosine kinase that is a key mediator of [...] (869 aa)
      0.967
HSPG2
heparan sulfate proteoglycan 2; This protein is an integral component of basement membranes. It [...] (4391 aa)
       0.909
RAPSN
receptor-associated protein of the synapse; Thought to play some role in anchoring or stabilizi [...] (412 aa)
       0.842
CHAT
choline acetyltransferase; Catalyzes the reversible synthesis of acetylcholine (ACh) from acety [...] (748 aa)
       0.836
DOK7
docking protein 7; Probable muscle-intrinsic activator of MUSK that plays an essential role in [...] (504 aa)
       0.817
CHRNE
cholinergic receptor, nicotinic, epsilon; After binding acetylcholine, the AChR responds by an [...] (493 aa)
       0.808
PRIMA1
proline rich membrane anchor 1; Required to anchor acetylcholinesterase (ACHE) to the basal lam [...] (153 aa)
       0.780
EWSR1
Ewing sarcoma breakpoint region 1; Might normally function as a repressor. EWS-fusion- proteins [...] (656 aa)
       0.768
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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