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  FOXC1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
FOXC1
forkhead box C1; Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees (553 aa)
(Homo sapiens)
Predicted Functional Partners:
PITX2
paired-like homeodomain 2; May play an important role in development and maintenance of anterio [...] (324 aa)
       0.970
DLL4
delta-like 4 (Drosophila); Plays a role in the Notch signaling pathway. Activates Notch-1 and N [...] (685 aa)
       0.925
HEY2
hairy/enhancer-of-split related with YRPW motif 2; Downstream effector of Notch signaling which [...] (337 aa)
       0.923
ALX4
ALX homeobox 4; Transcription factor involved in skull and limb development (411 aa)
       0.880
MSX2
msh homeobox 2; Probable morphogenetic role. May play a role in limb- pattern formation. In ost [...] (267 aa)
       0.880
PAX6
paired box 6; Transcription factor with important functions in the development of the eye, nose [...] (436 aa)
       0.870
FGF2
fibroblast growth factor 2 (basic); The heparin-binding growth factors are angiogenic agents in [...] (288 aa)
       0.846
FLNA
filamin A, alpha; Promotes orthogonal branching of actin filaments and links actin filaments to [...] (2647 aa)
       0.830
CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1; Cytochromes P450 are a group of heme-thi [...] (543 aa)
       0.828
CXCR4
chemokine (C-X-C motif) receptor 4; Receptor for the C-X-C chemokine CXCL12/SDF-1. Transduces a [...] (356 aa)
       0.817
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

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