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  IL2RA protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
IL2RA
interleukin 2 receptor, alpha; Receptor for interleukin-2 (272 aa)
(Homo sapiens)
Predicted Functional Partners:
IL2
interleukin 2; Produced by T-cells in response to antigenic or mitogenic stimulation, this prot [...] (153 aa)
     0.999
IL2RB
interleukin 2 receptor, beta; Receptor for interleukin-2. This beta subunit is involved in rece [...] (551 aa)
     0.999
IL2RG
interleukin 2 receptor, gamma (severe combined immunodeficiency); Common subunit for the recept [...] (369 aa)
     0.999
FOXP3
forkhead box P3; Probable transcription factor. Plays a critical role in the control of immune [...] (431 aa)
      0.998
JAK3
Janus kinase 3; Tyrosine kinase of the non-receptor type, involved in the interleukin-2 and int [...] (1124 aa)
      0.996
CD8A
CD8a molecule; Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing t [...] (235 aa)
      0.996
JAK1
Janus kinase 1; Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma [...] (1154 aa)
      0.995
IL15
interleukin 15; Cytokine that stimulates the proliferation of T- lymphocytes. Stimulation by IL [...] (162 aa)
       0.993
TNF
tumor necrosis factor (TNF superfamily, member 2); Cytokine that binds to TNFRSF1A/TNFR1 and TN [...] (233 aa)
       0.991
IL7
interleukin 7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid [...] (177 aa)
       0.991
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

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