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  CYP1A1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics (512 aa)
(Homo sapiens)
Predicted Functional Partners:
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic); Biotransformation enzyme that catalyzes the hydro [...] (455 aa)
      0.995
AHR
aryl hydrocarbon receptor; Ligand-activated transcriptional activator. Binds to the XRE promote [...] (848 aa)
       0.990
ARNT
aryl hydrocarbon receptor nuclear translocator; Required for activity of the Ah (dioxin) recept [...] (789 aa)
       0.989
GSTM1
glutathione S-transferase mu 1; Conjugation of reduced glutathione to a wide number of exogenou [...] (218 aa)
      0.987
COMT
catechol-O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of cat [...] (271 aa)
      0.984
GSTP1
glutathione S-transferase pi 1; Conjugation of reduced glutathione to a wide number of exogenou [...] (210 aa)
      0.982
GSTT2
glutathione S-transferase theta 2; Conjugation of reduced glutathione to a wide number of exoge [...] (244 aa)
      0.977
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1; UDPGT is of major importance in the conju [...] (533 aa)
      0.977
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6; UDPGT is of major importance in the conju [...] (532 aa)
      0.976
GSTM3
glutathione S-transferase mu 3 (brain); Conjugation of reduced glutathione to a wide number of [...] (225 aa)
      0.976
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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