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  CST3 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CST3
cystatin C; As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity (146 aa)
(Homo sapiens)
Predicted Functional Partners:
CTSB
cathepsin B; Thiol protease which is believed to participate in intracellular degradation and t [...] (339 aa)
      0.992
CTSL1
cathepsin L1; Important for the overall degradation of proteins in lysosomes (333 aa)
      0.981
CTSS
cathepsin S; Thiol protease. Key protease responsible for the removal of the invariant chain fr [...] (331 aa)
      0.973
CSTB
cystatin B (stefin B); This is an intracellular thiol proteinase inhibitor. Tightly binding rev [...] (98 aa)
      0.913
APOE
apolipoprotein E; Mediates the binding, internalization, and catabolism of lipoprotein particle [...] (317 aa)
       0.912
CTSD
cathepsin D; Acid protease active in intracellular protein breakdown. Involved in the pathogene [...] (412 aa)
     0.911
ITM2B
integral membrane protein 2B (266 aa)
       0.893
APP
amyloid beta (A4) precursor protein; N-APP binds TNFRSF21 triggering caspase activation and deg [...] (770 aa)
       0.889
CTSK
cathepsin K; Closely involved in osteoclastic bone resorption and may participate partially in [...] (329 aa)
       0.877
B2M
beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved [...] (119 aa)
       0.848
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
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additional (white) nodes

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