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  WAS protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia); Effector protein for Rho-type GTPases, providing a link with the Arp2/3 complex that regulates the structure and dynamics of the actin cytoskeleton. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function (502 aa)
(Homo sapiens)
Predicted Functional Partners:
CDC42
cell division cycle 42 (GTP binding protein, 25kDa); Plasma membrane-associated small GTPase wh [...] (191 aa)
     0.999
NCK1
NCK adaptor protein 1; Adapter protein which associates with tyrosine- phosphorylated growth fa [...] (377 aa)
     0.999
WIPF1
WAS/WASL interacting protein family, member 1; May have direct activity on the actin cytoskelet [...] (503 aa)
      0.999
FYN
FYN oncogene related to SRC, FGR, YES; Implicated in the control of cell growth. Plays a role i [...] (537 aa)
      0.998
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa; Functions as component of the Arp2/3 compl [...] (178 aa)
     0.997
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1; Involved in regulation of the actin [...] (416 aa)
      0.995
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa; Functions as actin-binding component of th [...] (300 aa)
     0.994
ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa; Functions as component of the Arp2/3 compl [...] (151 aa)
      0.991
WIPF2
WAS/WASL interacting protein family, member 2; Plays an active role in the formation of cell su [...] (440 aa)
      0.990
WASF1
WAS protein family, member 1; Downstream effector molecules involved in the transmission of sig [...] (559 aa)
       0.990
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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