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  PQBP1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PQBP1
polyglutamine binding protein 1; May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit (265 aa)
(Homo sapiens)
Predicted Functional Partners:
WBP11
WW domain binding protein 11; May play a role in the regulation of pre-mRNA processing (641 aa)
      0.993
TXNL4A
thioredoxin-like 4A; Essential role in pre-mRNA splicing (142 aa)
      0.972
SF3A2
splicing factor 3a, subunit 2, 66kDa; Subunit of the splicing factor SF3A required for 'A' comp [...] (464 aa)
       0.968
POU3F2
POU class 3 homeobox 2; Transcription factor that binds preferentially to the recognition seque [...] (443 aa)
      0.882
MYH3
myosin, heavy chain 3, skeletal muscle, embryonic; Muscle contraction (1940 aa)
       0.866
ATXN1
ataxin 1; Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polygluta [...] (815 aa)
      0.859
FTSJ1
FtsJ homolog 1 (E. coli) (329 aa)
       0.839
DLG3
discs, large homolog 3 (Drosophila); Required for learning most likely through its role in syna [...] (817 aa)
       0.810
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member [...] (1480 aa)
       0.800
HSPB1
heat shock 27kDa protein 1; Involved in stress resistance and actin organization (205 aa)
       0.786
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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