F7 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.

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coagulation factor VII (serum prothrombin conversion accelerator); Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium (466 aa)
(Homo sapiens)
Predicted Functional Partners:
coagulation factor III (thromboplastin, tissue factor); Initiates blood coagulation by forming [...] (295 aa)
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor); Inhibits factor [...] (304 aa)
gamma-glutamyl carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residue [...] (758 aa)
coagulation factor V (proaccelerin, labile factor); Central regulator of hemostasis. It serves [...] (2224 aa)
coagulation factor IX; Factor IX is a vitamin K-dependent plasma protein that participates in t [...] (461 aa)
coagulation factor X; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin [...] (488 aa)
apolipoprotein B (including Ag(x) antigen); Apolipoprotein B is a major protein constituent of [...] (4563 aa)
coagulation factor VIII, procoagulant component; Factor VIII, along with calcium and phospholip [...] (2351 aa)
bradykinin receptor B2; Receptor for bradykinin. It is associated with G proteins that activate [...] (391 aa)
furin (paired basic amino acid cleaving enzyme); Furin is likely to represent the ubiquitous en [...] (794 aa)
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Active Prediction Methods:
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Co-expression Experiments Databases Textmining
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