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  F7 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
F7
coagulation factor VII (serum prothrombin conversion accelerator); Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium (466 aa)
(Homo sapiens)
Predicted Functional Partners:
F3
coagulation factor III (thromboplastin, tissue factor); Initiates blood coagulation by forming [...] (295 aa)
     0.999
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor); Inhibits factor [...] (304 aa)
      0.993
GGCX
gamma-glutamyl carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residue [...] (758 aa)
     0.991
F5
coagulation factor V (proaccelerin, labile factor); Central regulator of hemostasis. It serves [...] (2224 aa)
       0.978
F9
coagulation factor IX; Factor IX is a vitamin K-dependent plasma protein that participates in t [...] (461 aa)
   0.964
F10
coagulation factor X; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin [...] (488 aa)
   0.964
APOB
apolipoprotein B (including Ag(x) antigen); Apolipoprotein B is a major protein constituent of [...] (4563 aa)
       0.949
F8
coagulation factor VIII, procoagulant component; Factor VIII, along with calcium and phospholip [...] (2351 aa)
       0.914
BDKRB2
bradykinin receptor B2; Receptor for bradykinin. It is associated with G proteins that activate [...] (391 aa)
       0.899
FURIN
furin (paired basic amino acid cleaving enzyme); Furin is likely to represent the ubiquitous en [...] (794 aa)
      0.899
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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