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  GSN protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
GSN
gelsolin (amyloidosis, Finnish type); Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed (782 aa)
(Homo sapiens)
Predicted Functional Partners:
CASP3
caspase 3, apoptosis-related cysteine peptidase; Involved in the activation cascade of caspases [...] (277 aa)
     0.990
VASP
vasodilator-stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved [...] (380 aa)
      0.969
MYH14
myosin, heavy chain 14, non-muscle; Cellular myosin that appears to play a role in cytokinesis, [...] (2003 aa)
       0.965
TNIK
TRAF2 and NCK interacting kinase; Serine/threonine kinase that acts as an essential activator o [...] (1360 aa)
      0.964
PLCG1
phospholipase C, gamma 1; PLC-gamma is a major substrate for heparin-binding growth factor 1 (a [...] (1291 aa)
     0.963
EGF
epidermal growth factor (beta-urogastrone); EGF stimulates the growth of various epidermal and [...] (1207 aa)
      0.959
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide; Phosphorylates PtdIns, PtdIns4P and Pt [...] (1068 aa)
     0.956
TPM1
tropomyosin 1 (alpha); Binds to actin filaments in muscle and non-muscle cells. Plays a central [...] (284 aa)
       0.954
FN1
fibronectin 1; Fibronectins bind cell surfaces and various compounds including collagen, fibrin [...] (2477 aa)
      0.940
ACTA1
actin, alpha 1, skeletal muscle; Actins are highly conserved proteins that are involved in vari [...] (377 aa)
      0.939
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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