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  POU3F1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
POU3F1
POU class 3 homeobox 1; Transcription factor that binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a nonconserved spacer region of 0, 2, or 3 nucleotides. Positively regulates the genes under the control of corticotropin-releasing hormone (CRH) and CRH II promoters (By similarity) (451 aa)
(Homo sapiens)
Predicted Functional Partners:
EGR2
early growth response 2; Sequence-specific DNA-binding transcription factor. Binds to two speci [...] (476 aa)
       0.950
CCDC6
coiled-coil domain containing 6 (474 aa)
       0.768
CYB5D2
cytochrome b5 domain containing 2 (264 aa)
       0.749
SCIN
scinderin; Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulato [...] (715 aa)
       0.704
FAM48A
family with sequence similarity 48, member A; Required for MAP kinase p38 (MAPK11, MAPK12, MAPK [...] (779 aa)
       0.679
HMGB2
high-mobility group box 2; Binds preferentially single-stranded DNA and unwinds double stranded [...] (209 aa)
      0.677
ASCL1
achaete-scute complex homolog 1 (Drosophila); May play a role at early stages of development of [...] (236 aa)
       0.658
PMP22
peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in t [...] (160 aa)
       0.655
MBP
myelin basic protein; The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the [...] (304 aa)
       0.653
HMGA1
high mobility group AT-hook 1; HMG-I/Y bind preferentially to the minor groove of A+T rich regi [...] (107 aa)
       0.619
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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