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  HEYL protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
HEYL
hairy/enhancer-of-split related with YRPW motif-like; Downstream effector of Notch signaling which may be required for cardiovascular development (By similarity). Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (By similarity). Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 (328 aa)
(Homo sapiens)
Predicted Functional Partners:
RRBP1
ribosome binding protein 1 homolog 180kDa (dog); Acts as a ribosome receptor and mediates inter [...] (977 aa)
       0.877
NOTCH1
Notch homolog 1, translocation-associated (Drosophila); Functions as a receptor for membrane-bo [...] (2555 aa)
       0.782
DLL3
delta-like 3 (Drosophila); Inhibits primary neurogenesis. May be required to divert neurons alo [...] (618 aa)
       0.754
DLL4
delta-like 4 (Drosophila); Plays a role in the Notch signaling pathway. Activates Notch-1 and N [...] (685 aa)
       0.742
JAG2
jagged 2; Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb [...] (1238 aa)
       0.732
HHIPL2
HHIP-like 2 (724 aa)
       0.696
HHIPL1
HHIP-like 1 (782 aa)
       0.696
HPCAL4
hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphoryl [...] (191 aa)
       0.657
NOTCH3
Notch homolog 3 (Drosophila); Functions as a receptor for membrane-bound ligands Jagged1, Jagge [...] (2321 aa)
       0.649
NOTCH2
Notch homolog 2 (Drosophila); Functions as a receptor for membrane-bound ligands Jagged1, Jagge [...] (2471 aa)
       0.603
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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