PTP4A1 protein (Homo sapiens) - STRING interaction network

PTP4A1 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	PTP4A1	protein tyrosine phosphatase type IVA, member 1; Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis (173 aa)
		(Homo sapiens)
Predicted Functional Partners:
	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (536 aa)		•	•	0.983
	ATF7	activating transcription factor 7; Binds the cAMP response element (CRE) (consensus- 5'- GTGACG [...] (494 aa)	•		•	0.980
	EGR1	early growth response 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5' [...] (543 aa)		•	•	0.957
	ATF5	activating transcription factor 5; Transcriptional activator which binds the cAMP response elem [...] (282 aa)		•	•	0.950
	BCAR1	breast cancer anti-estrogen resistance 1; Docking protein which plays a central coordinating ro [...] (870 aa)			•	0.943
	CCNA2	cyclin A2; Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosi [...] (432 aa)		•	•	0.922
	RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); Plasma [...] (211 aa)		•	•	0.914
	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1); May be the important intermediate by which p5 [...] (164 aa)		•		0.899
	PTS	6-pyruvoyltetrahydropterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an es [...] (145 aa)			•	0.858
	TP53	tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apo [...] (393 aa)			•	0.846

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes

Server load: medium (49%)

Permalink