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  DPYD protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
DPYD
dihydropyrimidine dehydrogenase; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil (1025 aa)
(Homo sapiens)
Predicted Functional Partners:
DPYS
dihydropyrimidinase; Catalyzes the second step of the reductive pyrimidine degradation, the rev [...] (519 aa)
     0.988
TYMP
thymidine phosphorylase; May have a role in maintaining the integrity of the blood vessels. Has [...] (482 aa)
      0.977
UMPS
uridine monophosphate synthetase (480 aa)
      0.977
UPP1
uridine phosphorylase 1; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyu [...] (310 aa)
      0.976
UPB1
ureidopropionase, beta; Converts N-carbamyl-beta-aminoisobutyric acid and N- carbamyl-beta-alan [...] (384 aa)
    0.969
TYMS
thymidylate synthetase (313 aa)
       0.947
CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 7; Exhibits a coumarin 7-hydroxylase activi [...] (494 aa)
      0.943
PNP
purine nucleoside phosphorylase (289 aa)
      0.907
UPP2
uridine phosphorylase 2; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyu [...] (374 aa)
       0.899
UPRT
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) (309 aa)
       0.899
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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