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  DKC1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
DKC1
small nucleolar RNA, H/ACA box 56; Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse t [...] (514 aa)
(Homo sapiens)
Predicted Functional Partners:
GAR1
GAR1 ribonucleoprotein homolog (yeast); Required for ribosome biogenesis and telomere maintenan [...] (217 aa)
     0.999
NHP2
NHP2 ribonucleoprotein homolog (yeast); Required for ribosome biogenesis and telomere maintenan [...] (153 aa)
   0.999
TERT
telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the re [...] (1132 aa)
     0.998
RUVBL1
RuvB-like 1 (E. coli); Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA h [...] (456 aa)
    0.998
NOP10
NOP10 ribonucleoprotein homolog (yeast); Required for ribosome biogenesis and telomere maintena [...] (64 aa)
     0.996
WRAP53
WD repeat containing, antisense to TP53; Essential component of the telomerase holoenzyme compl [...] (548 aa)
      0.993
NOLC1
nucleolar and coiled-body phosphoprotein 1; Related to nucleologenesis, may play a role in the [...] (699 aa)
      0.991
RUVBL2
RuvB-like 2 (E. coli); Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA h [...] (463 aa)
    0.987
SHQ1
SHQ1 homolog (S. cerevisiae) (577 aa)
     0.986
FBLL1
fibrillarin-like 1; Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-met [...] (334 aa)
    0.983
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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