LMNA protein (Homo sapiens) - STRING interaction network

LMNA protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	LMNA	lamin A/C; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals (664 aa)
		(Homo sapiens)
Predicted Functional Partners:
	EMD	emerin; Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates a [...] (254 aa)	•		•		0.999
	NARF	nuclear prelamin A recognition factor (456 aa)	•	•	•		0.985
	BANF1	barrier to autointegration factor 1; Plays fundamental roles in nuclear assembly, chromatin org [...] (89 aa)	•		•		0.984
	ZNF239	zinc finger protein 239; May be involved in transcriptional regulation (458 aa)	•		•		0.975
	CASP6	caspase 6, apoptosis-related cysteine peptidase; Involved in the activation cascade of caspases [...] (293 aa)	•	•	•		0.973
	ZMPSTE24	zinc metallopeptidase (STE24 homolog, S. cerevisiae); Proteolytically removes the C-terminal th [...] (475 aa)			•		0.971
	LMNB1	lamin B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic sid [...] (586 aa)	•	•	•	•	0.961
	LMNB2	lamin B2; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic sid [...] (600 aa)	•	•	•	•	0.961
	TMPO	thymopoietin; May help direct the assembly of the nuclear lamina and thereby help maintain the [...] (694 aa)	•		•		0.958
	LAMA2	laminin, alpha 2; Binding to cells via a high affinity receptor, laminin is thought to mediate [...] (3122 aa)			•		0.952

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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