version_number_image
  LMNA protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
LMNA
lamin A/C; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals (664 aa)
(Homo sapiens)
Predicted Functional Partners:
EMD
emerin; Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates a [...] (254 aa)
      0.999
NARF
nuclear prelamin A recognition factor (456 aa)
     0.985
BANF1
barrier to autointegration factor 1; Plays fundamental roles in nuclear assembly, chromatin org [...] (89 aa)
      0.984
ZNF239
zinc finger protein 239; May be involved in transcriptional regulation (458 aa)
      0.975
CASP6
caspase 6, apoptosis-related cysteine peptidase; Involved in the activation cascade of caspases [...] (293 aa)
     0.973
ZMPSTE24
zinc metallopeptidase (STE24 homolog, S. cerevisiae); Proteolytically removes the C-terminal th [...] (475 aa)
       0.971
LMNB1
lamin B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic sid [...] (586 aa)
    0.961
LMNB2
lamin B2; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic sid [...] (600 aa)
    0.961
TMPO
thymopoietin; May help direct the assembly of the nuclear lamina and thereby help maintain the [...] (694 aa)
      0.958
LAMA2
laminin, alpha 2; Binding to cells via a high affinity receptor, laminin is thought to mediate [...] (3122 aa)
       0.952
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (4%)
Permalink