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  NR1I3 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
NR1I3
nuclear receptor subfamily 1, group I, member 3; Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element (357 aa)
(Homo sapiens)
Predicted Functional Partners:
RXRA
retinoid X receptor, alpha; Nuclear hormone receptor. Involved in the retinoic acid response pa [...] (462 aa)
     0.967
CYP1A2
cytochrome P450, family 1, subfamily A, polypeptide 2; Cytochromes P450 are a group of heme-thi [...] (516 aa)
       0.966
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1; Cytochromes P450 are a group of heme-thi [...] (512 aa)
       0.965
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6; Cytochromes P450 are a group of heme-thi [...] (491 aa)
       0.954
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1; UDPGT is of major importance in the conju [...] (533 aa)
       0.954
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19; Cytochromes P450 are a group of heme-th [...] (490 aa)
       0.947
SLC45A2
solute carrier family 45, member 2; Melanocyte differentiation antigen. May transport substance [...] (530 aa)
       0.944
NR0B2
nuclear receptor subfamily 0, group B, member 2; Acts as a negative regulator of receptor-depen [...] (257 aa)
      0.927
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4; Cytochromes P450 are a group of heme-thi [...] (503 aa)
       0.901
EGFL8
EGF-like-domain, multiple 8 (293 aa)
       0.899
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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