NR1I3 protein (Homo sapiens) - STRING interaction network

NR1I3 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	NR1I3	nuclear receptor subfamily 1, group I, member 3; Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element (357 aa)
		(Homo sapiens)
Predicted Functional Partners:
	RXRA	retinoid X receptor, alpha; Nuclear hormone receptor. Involved in the retinoic acid response pa [...] (462 aa)	•		•	•	0.967
	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2; Cytochromes P450 are a group of heme-thi [...] (516 aa)			•		0.966
	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1; Cytochromes P450 are a group of heme-thi [...] (512 aa)			•		0.965
	CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6; Cytochromes P450 are a group of heme-thi [...] (491 aa)			•		0.954
	UGT1A1	UDP glucuronosyltransferase 1 family, polypeptide A1; UDPGT is of major importance in the conju [...] (533 aa)			•		0.954
	CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19; Cytochromes P450 are a group of heme-th [...] (490 aa)			•		0.947
	SLC45A2	solute carrier family 45, member 2; Melanocyte differentiation antigen. May transport substance [...] (530 aa)			•		0.944
	NR0B2	nuclear receptor subfamily 0, group B, member 2; Acts as a negative regulator of receptor-depen [...] (257 aa)	•		•		0.927
	CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4; Cytochromes P450 are a group of heme-thi [...] (503 aa)			•		0.901
	EGFL8	EGF-like-domain, multiple 8 (293 aa)		•			0.899

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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