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  PTGS2 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity (604 aa)
(Homo sapiens)
Predicted Functional Partners:
IL1B
interleukin 1, beta; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation [...] (269 aa)
      0.997
PLA2G1B
phospholipase A2, group IB (pancreas); PA2 catalyzes the calcium-dependent hydrolysis of the 2- [...] (148 aa)
      0.997
FOS
FBJ murine osteosarcoma viral oncogene homolog; Nuclear phosphoprotein which forms a tight but [...] (380 aa)
      0.996
IL6
interleukin 6 (interferon, beta 2); Cytokine with a wide variety of biological functions. It is [...] (212 aa)
      0.996
PTGDS
prostaglandin D2 synthase 21kDa (brain); Catalyzes the conversion of PGH2 to PGD2, a prostaglan [...] (190 aa)
      0.995
JUN
jun oncogene; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'- [...] (331 aa)
      0.995
MAPK14
mitogen-activated protein kinase 14; Responds to activation by environmental stress, pro- infla [...] (360 aa)
      0.995
MAPK3
mitogen-activated protein kinase 3; Involved in both the initiation and regulation of meiosis, [...] (379 aa)
      0.995
PTGES3
prostaglandin E synthase 3 (cytosolic); Molecular chaperone that localizes to genomic response [...] (160 aa)
      0.995
MAPK1
mitogen-activated protein kinase 1; Involved in both the initiation and regulation of meiosis, [...] (360 aa)
      0.993
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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