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  POU3F3 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
POU3F3
POU class 3 homeobox 3; Transcription factor that binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a nonconserved spacer region of 0, 2, or 3 nucleotides. Positively regulates the genes under the control of corticotropin-releasing hormone (CRH) and CRH II promoters (By similarity) (500 aa)
(Homo sapiens)
Predicted Functional Partners:
ASCL1
achaete-scute complex homolog 1 (Drosophila); May play a role at early stages of development of [...] (236 aa)
       0.937
SOX10
SRY (sex determining region Y)-box 10; Transcription factor that seems to function synergistica [...] (466 aa)
      0.892
EGR2
early growth response 2; Sequence-specific DNA-binding transcription factor. Binds to two speci [...] (476 aa)
       0.871
SOX11
SRY (sex determining region Y)-box 11; Probably important in the developing nervous system. May [...] (441 aa)
      0.865
DLL1
delta-like 1 (Drosophila); Acts as a ligand for Notch receptors. Blocks the differentiation of [...] (723 aa)
       0.819
NOTCH1
Notch homolog 1, translocation-associated (Drosophila); Functions as a receptor for membrane-bo [...] (2555 aa)
       0.786
MYT1L
myelin transcription factor 1-like; May function as a panneural transcription factor associated [...] (1184 aa)
       0.750
FAM48A
family with sequence similarity 48, member A; Required for MAP kinase p38 (MAPK11, MAPK12, MAPK [...] (779 aa)
       0.679
DLX1
distal-less homeobox 1; Likely to play a regulatory role in the development of the ventral fore [...] (255 aa)
       0.660
LHX2
LIM homeobox 2; Transcriptional regulatory protein involved in the control of cell differentiat [...] (406 aa)
       0.657
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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