HLA-DR15 protein (Homo sapiens) - STRING interaction network

HLA-DR15 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	HLA-DR15	HLA class II histocompatibility antigen, DRB1-15 beta chain Precursor (MHC class I antigen DRB1*15)(DW2.2/DR2.2) (266 aa)
		(Homo sapiens)
Predicted Functional Partners:
	CD4	CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regul [...] (458 aa)		•	•	0.954
	CD86	CD86 molecule; Receptor involved in the costimulatory signal essential for T-lymphocyte prolife [...] (329 aa)		•	•	0.930
	CD80	CD80 molecule; Involved in the costimulatory signal essential for T- lymphocyte activation. T-c [...] (288 aa)		•	•	0.928
	IFNG	interferon, gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamm [...] (166 aa)		•	•	0.924
	TRBC2	T cell receptor beta constant 2 (179 aa)	•			0.899
	DBNL	drebrin-like; Actin-binding adapter protein. May act as a common effector of antigen receptor-s [...] (439 aa)		•		0.899
	SHC1	SHC (Src homology 2 domain containing) transforming protein 1; Signaling adapter that couples a [...] (584 aa)		•		0.899
	ITK	IL2-inducible T-cell kinase; Plays a role in T-cell proliferation and differentiation (620 aa)		•		0.899
	PTPN6	protein tyrosine phosphatase, non-receptor type 6; Plays a key role in hematopoiesis. This PTPa [...] (624 aa)		•		0.899
	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to env [...] (821 aa)		•		0.899

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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