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  RYR1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
RYR1
ryanodine receptor 1 (skeletal); Communication between transverse-tubules and sarcoplasmic reticulum. Contraction of skeletal muscle is triggered by release of calcium ions from SR following depolarization of T-tubules (5038 aa)
(Homo sapiens)
Predicted Functional Partners:
TRDN
triadin; May be involved in anchoring calsequestrin to the junctional sarcoplasmic reticulum an [...] (731 aa)
      0.999
FKBP1A
FK506 binding protein 1A, 12kDa; May play a role in modulation of ryanodine receptor isoform-1 [...] (108 aa)
      0.998
HOMER1
homer homolog 1 (Drosophila); Postsynaptic density scaffolding protein. Binds and cross-links c [...] (354 aa)
      0.996
CALM1
calmodulin 1 (phosphorylase kinase, delta); Calmodulin mediates the control of a large number o [...] (149 aa)
      0.985
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit; Voltage-sensitive calcium channel [...] (1873 aa)
      0.981
S100A1
S100 calcium binding protein A1; Weakly binds calcium but binds zinc very tightly- distinct bin [...] (94 aa)
      0.975
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1; The alpha-2/delta subunit of volta [...] (1091 aa)
       0.965
QDPR
quinoid dihydropteridine reductase; The product of this enzyme, tetrahydrobiopterin (BH-4), is [...] (244 aa)
       0.963
KRIT1
KRIT1, ankyrin repeat containing (736 aa)
       0.953
CAMK2B
calcium/calmodulin-dependent protein kinase II beta; CaM-kinase II (CAMK2) is a prominent kinas [...] (666 aa)
       0.947
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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