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  NF1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
NF1
neurofibromin 1; Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity (2839 aa)
(Homo sapiens)
Predicted Functional Partners:
NF2
neurofibromin 2 (merlin); Probably acts as a membrane stabilizing protein. May inhibit PI3 kina [...] (595 aa)
       0.993
TP53
tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apo [...] (393 aa)
       0.987
HRAS
v-Ha-ras Harvey rat sarcoma viral oncogene homolog; Ras proteins bind GDP/GTP and possess intri [...] (189 aa)
      0.984
SP1
Sp1 transcription factor; Transcription factor that can activate or repress transcription in re [...] (785 aa)
       0.973
EVI2A
ecotropic viral integration site 2A; May complex with itself or/and other proteins within the m [...] (259 aa)
       0.957
EVI2B
ecotropic viral integration site 2B (448 aa)
       0.956
OMG
oligodendrocyte myelin glycoprotein; Cell adhesion molecule contributing to the interactive pro [...] (440 aa)
       0.955
FOXM1
forkhead box M1; Transcriptional activatory factor. May play a role in the control of cell prol [...] (801 aa)
       0.949
JUN
jun oncogene; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'- [...] (331 aa)
       0.947
KRAS
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog; Ras proteins bind GDP/GTP and possess int [...] (189 aa)
       0.944
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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