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  ATP2A1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (1001 aa)
(Homo sapiens)
Predicted Functional Partners:
PLN
phospholamban; Phospholamban has been postulated to regulate the activity of the calcium pump o [...] (52 aa)
     0.998
SLN
sarcolipin (31 aa)
     0.994
DNAH8
dynein, axonemal, heavy chain 8; Force generating protein of respiratory cilia. Produces force [...] (4490 aa)
       0.958
RYR2
ryanodine receptor 2 (cardiac); Communication between transverse-tubules and sarcoplasmic retic [...] (4965 aa)
      0.927
AKAP6
A kinase (PRKA) anchor protein 6; Binds to type II regulatory subunits of protein kinase A and [...] (2319 aa)
      0.924
IRS2
insulin receptor substrate 2; May mediate the control of various cellular processes by insulin (1338 aa)
      0.919
IRS1
insulin receptor substrate 1; May mediate the control of various cellular processes by insulin. [...] (1242 aa)
      0.919
FKBP1B
FK506 binding protein 1B, 12.6 kDa; Associates with the ryanodine receptor (RYR-2) in cardiac m [...] (108 aa)
      0.916
TRPC4
transient receptor potential cation channel, subfamily C, member 4; Thought to form a receptor- [...] (982 aa)
      0.902
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4; Reversibly stimulates the variable phos [...] (323 aa)
       0.899
 
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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