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  DHCR7 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
DHCR7
7-dehydrocholesterol reductase; Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC) (475 aa)
(Homo sapiens)
Predicted Functional Partners:
SC5DL
sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like; Catalyzes a dehydro [...] (299 aa)
    0.984
DHCR24
24-dehydrocholesterol reductase; Catalyzes the reduction of the delta-24 double bond of sterol [...] (516 aa)
     0.981
EBP
emopamil binding protein (sterol isomerase); Catalyzes the conversion of Delta(8)-sterols to th [...] (230 aa)
      0.958
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1; Potassium c [...] (1178 aa)
       0.944
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1; Catalyzes the first step in the oxidati [...] (531 aa)
      0.934
CEL
carboxyl ester lipase (bile salt-stimulated lipase); Catalyzes fat and vitamin absorption. Acts [...] (756 aa)
       0.899
SOAT1
sterol O-acyltransferase 1; Catalyzes the formation of fatty acid-cholesterol esters. Plays a r [...] (550 aa)
       0.899
LIPA
lipase A, lysosomal acid, cholesterol esterase; Crucial for the intracellular hydrolysis of cho [...] (399 aa)
       0.899
SOAT2
sterol O-acyltransferase 2; Plays a role in lipoprotein assembly and dietary cholesterol absorp [...] (522 aa)
       0.899
NSDHL
NAD(P) dependent steroid dehydrogenase-like (373 aa)
     0.892
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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