TCF4 protein (Homo sapiens) - STRING interaction network

TCF4 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	TCF4	transcription factor 4; Transcription factor that binds to the immunoglobulin enchancer Mu-E5/KE5-motif. Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription (By similarity). Preferentially binds to either 5'- ACANNTGT-3' or 5'-CCANNTGG-3' (671 aa)
		(Homo sapiens)
Predicted Functional Partners:
	CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa; Involved in the regulation of cell adhesi [...] (781 aa)	•	•	0.999
	TAL1	T-cell acute lymphocytic leukemia 1; Implicated in the genesis of hemopoietic malignancies. It [...] (331 aa)	•	•	0.996
	ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein; ID (inhibitor of DNA bi [...] (155 aa)	•	•	0.994
	ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein; ID (inhibitor of DNA bi [...] (134 aa)	•	•	0.973
	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box); Participates in the Wnt signaling pat [...] (596 aa)		•	0.968
	ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein; ID (inhibitor of DNA bi [...] (119 aa)	•	•	0.964
	CCND1	cyclin D1; Essential for the control of the cell cycle at the G1/S (start) transition (295 aa)		•	0.960
	MYC	v-myc myelocytomatosis viral oncogene homolog (avian); Participates in the regulation of gene t [...] (454 aa)		•	0.953
	JUN	jun oncogene; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'- [...] (331 aa)	•	•	0.952
	BIRC5	baculoviral IAP repeat-containing 5; Component of the chromosomal passenger complex (CPC), a co [...] (165 aa)		•	0.936

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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