version_number_image
  SFTPB protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
SFTPB
surfactant protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter (381 aa)
(Homo sapiens)
Predicted Functional Partners:
SFTPC
surfactant protein C; Pulmonary surfactant associated proteins promote alveolar stability by lo [...] (197 aa)
      0.988
SFTPD
surfactant protein D; Contributes to the lung's defense against inhaled microorganisms. May par [...] (375 aa)
      0.973
SFTPA1
surfactant protein A1; In presence of calcium ions, it binds to surfactant phospholipids and co [...] (248 aa)
      0.968
SFTPA2
surfactant protein A2; In presence of calcium ions, it binds to surfactant phospholipids and co [...] (248 aa)
      0.964
NKX2-1
NK2 homeobox 1; Transcription factor that binds and activates the promoter of thyroid specific [...] (401 aa)
       0.962
FOXA1
forkhead box A1; Transcription activator for a number of liver genes such as AFP, albumin, tyro [...] (472 aa)
       0.913
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3; Plays an important role in the formation o [...] (1704 aa)
       0.911
SP1
Sp1 transcription factor; Transcription factor that can activate or repress transcription in re [...] (785 aa)
       0.899
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin); Binds phosphatidylcholine, phosphatidylinosit [...] (91 aa)
      0.877
RARS
arginyl-tRNA synthetase (660 aa)
       0.870
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (6%)
Permalink