SFTPB protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
surfactant protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter (381 aa)
(Homo sapiens)
Predicted Functional Partners:
surfactant protein C; Pulmonary surfactant associated proteins promote alveolar stability by lo [...] (197 aa)
surfactant protein D; Contributes to the lung's defense against inhaled microorganisms. May par [...] (375 aa)
surfactant protein A1; In presence of calcium ions, it binds to surfactant phospholipids and co [...] (248 aa)
surfactant protein A2; In presence of calcium ions, it binds to surfactant phospholipids and co [...] (248 aa)
NK2 homeobox 1; Transcription factor that binds and activates the promoter of thyroid specific [...] (401 aa)
forkhead box A1; Transcription activator for a number of liver genes such as AFP, albumin, tyro [...] (472 aa)
ATP-binding cassette, sub-family A (ABC1), member 3; Plays an important role in the formation o [...] (1704 aa)
Sp1 transcription factor; Transcription factor that can activate or repress transcription in re [...] (785 aa)
secretoglobin, family 1A, member 1 (uteroglobin); Binds phosphatidylcholine, phosphatidylinosit [...] (91 aa)
arginyl-tRNA synthetase (660 aa)
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
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additional (white) nodes

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