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  DOK7 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
DOK7
docking protein 7; Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK (By similarity) (504 aa)
(Homo sapiens)
Predicted Functional Partners:
MUSK
muscle, skeletal, receptor tyrosine kinase; Receptor tyrosine kinase that is a key mediator of [...] (869 aa)
      0.993
RAPSN
receptor-associated protein of the synapse; Thought to play some role in anchoring or stabilizi [...] (412 aa)
       0.961
AGRN
agrin; Component of the basal lamina that causes the aggregation of acetylcholine receptors and [...] (2045 aa)
       0.955
ACHE
acetylcholinesterase (Yt blood group); Terminates signal transduction at the neuromuscular junc [...] (617 aa)
       0.844
COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase; An [...] (455 aa)
       0.817
CHRNE
cholinergic receptor, nicotinic, epsilon; After binding acetylcholine, the AChR responds by an [...] (493 aa)
       0.812
CST7
cystatin F (leukocystatin); Inhibits papain and cathepsin L but with affinities lower than othe [...] (167 aa)
       0.789
BCHE
butyrylcholinesterase (602 aa)
       0.782
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle); After binding acetylcholine, the AChR respon [...] (482 aa)
       0.751
SCN4A
sodium channel, voltage-gated, type IV, alpha subunit; This protein mediates the voltage-depend [...] (1836 aa)
       0.709
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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