PSPC1 protein (Homo sapiens) - STRING interaction network

PSPC1 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	PSPC1	paraspeckle component 1; Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene transcription activity in Sertoli cell line (By similarity). Binds to poly(A), poly(G) and poly(U) RNA homopolymers (By similarity) (523 aa)
		(Homo sapiens)
Predicted Functional Partners:
	SFPQ	splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated); DNA- [...] (707 aa)		•	•	•	0.941
	PCNA	proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delt [...] (261 aa)		•			0.849
	AR	androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that re [...] (920 aa)		•	•		0.740
	NONO	non-POU domain containing, octamer-binding; DNA- and RNA binding protein, involved in several n [...] (471 aa)		•	•	•	0.705
	SMAD3	SMAD family member 3; Transcriptional modulator activated by TGF-beta (transforming growth fact [...] (425 aa)		•	•		0.613
	JAM2	junctional adhesion molecule 2; May play a role in the processes of lymphocyte homing to second [...] (298 aa)			•		0.599
	HNRNPK	microRNA 7-1; One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequence [...] (464 aa)	•		•		0.580
	RNF14	ring finger protein 14; Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin fro [...] (474 aa)			•		0.553
	TLE3	transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila); Transcriptional corepressor t [...] (772 aa)		•			0.543
	WBP4	WW domain binding protein 4 (formin binding protein 21); Promotes pre-mRNA splicing. A spliceos [...] (376 aa)		•			0.538

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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