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  XRCC3 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
XRCC3
X-ray repair complementing defective repair in Chinese hamster cells 3; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions (346 aa)
(Homo sapiens)
Predicted Functional Partners:
FANCG
Fanconi anemia, complementation group G; DNA repair protein that may operate in a postreplicati [...] (622 aa)
      0.995
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2; Involved in the homolog [...] (280 aa)
       0.992
RAD51C
RAD51 homolog C (S. cerevisiae); Involved in the homologous recombination repair (HRR) pathway [...] (376 aa)
    0.987
NAT2
N-acetyltransferase 2 (arylamine N-acetyltransferase); Participates in the detoxification of a [...] (290 aa)
       0.950
BRCA2
breast cancer 2, early onset; Involved in double-strand break repair and/or homologous recombin [...] (3418 aa)
       0.934
FANCD2
Fanconi anemia, complementation group D2; Required for maintenance of chromosomal stability. Pr [...] (1471 aa)
       0.914
INO80
INO80 homolog (S. cerevisiae); Putative DNA helicase component of the INO80 complex which remod [...] (1556 aa)
       0.865
BLM
Bloom syndrome, RecQ helicase-like; Participates in DNA replication and repair. Exhibits a magn [...] (1417 aa)
       0.852
BRCA1
breast cancer 1, early onset; The BRCA1-BARD1 heterodimer coordinates a diverse range of cellul [...] (1863 aa)
       0.845
XRCC4
X-ray repair complementing defective repair in Chinese hamster cells 4; Involved in DNA non-hom [...] (336 aa)
       0.837
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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