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  POU1F1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
POU1F1
POU class 1 homeobox 1; Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'- TAAAT-3' (317 aa)
(Homo sapiens)
Predicted Functional Partners:
PRL
prolactin; Prolactin acts primarily on the mammary gland by promoting lactation (227 aa)
      0.999
TSHB
thyroid stimulating hormone, beta; Indispensable for the control of thyroid structure and metab [...] (138 aa)
       0.992
GHRHR
growth hormone releasing hormone receptor; Receptor for GRF, coupled to G proteins which activa [...] (423 aa)
       0.968
GATA2
GATA binding protein 2; Transcriptional activator which regulates endothelin-1 gene expression [...] (480 aa)
      0.966
PITX2
paired-like homeodomain 2; May play an important role in development and maintenance of anterio [...] (324 aa)
       0.959
GH1
growth hormone 1; Plays an important role in growth control. Its major role in stimulating body [...] (217 aa)
       0.942
HESX1
HESX homeobox 1; Required for the normal development of the forebrain, eyes and other anterior [...] (185 aa)
       0.942
POMC
proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol (267 aa)
       0.925
PITX1
paired-like homeodomain 1; May play a role in the development of anterior structures, and in pa [...] (314 aa)
      0.918
IGHD
immunoglobulin heavy constant delta (430 aa)
       0.905
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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