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  EXT2 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
EXT2
exostoses (multiple) 2; Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor (718 aa)
(Homo sapiens)
Predicted Functional Partners:
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1; Essential bifunctional enzyme that c [...] (882 aa)
      0.987
EXT1
exostoses (multiple) 1; Glycosyltransferase required for the biosynthesis of heparan-sulfate. T [...] (746 aa)
    0.987
EXTL1
exostoses (multiple)-like 1; Probable glycosyltransferase (By similarity) (676 aa)
    0.917
EXTL2
exostoses (multiple)-like 2; Glycosyltransferase required for the biosynthesis of heparan-sulfa [...] (330 aa)
     0.916
EXTL3
exostoses (multiple)-like 3; Probable glycosyltransferase (By similarity) (919 aa)
     0.914
SLC30A8
solute carrier family 30 (zinc transporter), member 8; Facilitates the accumulation of zinc fro [...] (369 aa)
       0.901
NDST2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2; Essential bifunctional enzyme that c [...] (883 aa)
       0.899
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3; Essential bifunctional enzyme that c [...] (873 aa)
       0.899
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1; Transfers a sulfuryl group to an N-unsu [...] (406 aa)
       0.899
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4; Essential bifunctional enzyme that c [...] (872 aa)
       0.899
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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