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  PKLR protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PKLR
pyruvate kinase, liver and RBC; Plays a key role in glycolysis (By similarity) (574 aa)
(Homo sapiens)
Predicted Functional Partners:
PXN
paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion [...] (591 aa)
      0.984
ENO1
enolase 1, (alpha); Multifunctional enzyme that, as well as its role in glycolysis, plays a par [...] (434 aa)
    0.982
PCK2
phosphoenolpyruvate carboxykinase 2 (mitochondrial); Catalyzes the conversion of oxaloacetate ( [...] (640 aa)
      0.972
AK1
adenylate kinase 1; Catalyzes the reversible transfer of the terminal phosphate group between A [...] (194 aa)
      0.968
GPI
glucose phosphate isomerase; Besides it's role as a glycolytic enzyme, mammalian GPI can functi [...] (558 aa)
    0.962
GCK
glucokinase (hexokinase 4); Catalyzes the initial step in utilization of glucose by the beta-ce [...] (466 aa)
     0.956
HK1
hexokinase 1 (921 aa)
      0.944
ENO2
enolase 2 (gamma, neuronal); Has neurotrophic and neuroprotective properties on a broad spectru [...] (434 aa)
    0.942
ENO3
enolase 3 (beta, muscle); Appears to have a function in striated muscle development and regener [...] (434 aa)
    0.942
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1; The pyruvate dehydrogenase complex catalyzes the ov [...] (390 aa)
      0.932
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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