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  TRIO protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
TRIO
triple functional domain (PTPRF interacting); Promotes the exchange of GDP by GTP. Together with leukocyte antigen-related (LAR) protein, it could play a role in coordinating cell-matrix and cytoskeletal rearrangements necessary for cell migration and cell growth (3097 aa)
(Homo sapiens)
Predicted Functional Partners:
RAC1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); Plasma [...] (211 aa)
     0.998
RHOA
ras homolog gene family, member A; Regulates a signal transduction pathway linking plasma membr [...] (193 aa)
      0.988
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3); Plasma [...] (192 aa)
      0.925
RHOG
ras homolog gene family, member G (rho G); Required for the formation of membrane ruffles durin [...] (191 aa)
       0.925
PLEK
pleckstrin; Major protein kinase C substrate of platelets, its exact function is not known (350 aa)
       0.914
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast); Cadherins are calcium dependent cell adhesion pr [...] (796 aa)
       0.878
NTN1
netrin 1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its ass [...] (604 aa)
       0.861
PTPN3
protein tyrosine phosphatase, non-receptor type 3; May act at junctions between the membrane an [...] (913 aa)
       0.854
DNTT
deoxynucleotidyltransferase, terminal; Template-independent DNA polymerase which catalyzes the [...] (509 aa)
       0.824
CDC42
cell division cycle 42 (GTP binding protein, 25kDa); Plasma membrane-associated small GTPase wh [...] (191 aa)
       0.786
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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