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  PLCB1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific); The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (1216 aa)
(Homo sapiens)
Predicted Functional Partners:
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide; Guanine nucleotide-binding prote [...] (359 aa)
     0.995
PRKCD
protein kinase C, delta; This is calcium-independent, phospholipid-dependent, serine- and threo [...] (676 aa)
     0.968
PRKCA
protein kinase C, alpha; This is a calcium-activated, phospholipid-dependent, serine- and threo [...] (672 aa)
     0.955
DGKA
diacylglycerol kinase, alpha 80kDa; Upon cell stimulation converts the second messenger diacylg [...] (735 aa)
      0.950
DGKZ
diacylglycerol kinase, zeta 104kDa; Displays a strong preference for 1,2-diacylglycerols over 1 [...] (1117 aa)
      0.950
PLCG1
phospholipase C, gamma 1; PLC-gamma is a major substrate for heparin-binding growth factor 1 (a [...] (1291 aa)
     0.931
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O; Guanin [...] (354 aa)
      0.926
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific); The production of the second messenge [...] (1265 aa)
     0.925
GNG2
guanine nucleotide binding protein (G protein), gamma 2; Guanine nucleotide-binding proteins (G [...] (71 aa)
      0.924
PLCD1
phospholipase C, delta 1; The production of the second messenger molecules diacylglycerol (DAG) [...] (777 aa)
     0.913
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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