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  FIP1L1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
FIP1L1
FIP1 like 1 (S. cerevisiae); Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex (594 aa)
(Homo sapiens)
Predicted Functional Partners:
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide; Receptor that binds both PDGFA and [...] (1089 aa)
       0.938
IL5
interleukin 5 (colony-stimulating factor, eosinophil); Factor that induces terminal differentia [...] (134 aa)
       0.866
PDGFRB
platelet-derived growth factor receptor, beta polypeptide; Receptor that binds specifically to [...] (1106 aa)
       0.845
BCR
breakpoint cluster region; GTPase-activating protein for RAC1 and CDC42. Promotes the exchange [...] (1271 aa)
       0.815
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; This is the receptor for stem ce [...] (976 aa)
       0.814
FGFR1
fibroblast growth factor receptor 1; Receptor for basic fibroblast growth factor. Receptor for [...] (822 aa)
       0.812
TPSG1
tryptase gamma 1 (321 aa)
       0.788
CEL
carboxyl ester lipase (bile salt-stimulated lipase); Catalyzes fat and vitamin absorption. Acts [...] (756 aa)
       0.786
RRAGA
Ras-related GTP binding A; Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a [...] (313 aa)
       0.784
RHD
Rh blood group, D antigen; May be part of an oligomeric complex which is likely to have a trans [...] (417 aa)
       0.782
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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