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  PLCB4 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PLCB4
phospholipase C, beta 4; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This form has a role in retina signal transduction (1194 aa)
(Homo sapiens)
Predicted Functional Partners:
ITPR1
inositol 1,4,5-triphosphate receptor, type 1; Intracellular channel that mediates calcium relea [...] (2710 aa)
      0.921
ITPR2
inositol 1,4,5-triphosphate receptor, type 2; Receptor for inositol 1,4,5-trisphosphate, a seco [...] (2701 aa)
      0.921
ITPR3
inositol 1,4,5-triphosphate receptor, type 3; Receptor for inositol 1,4,5-trisphosphate, a seco [...] (2671 aa)
      0.921
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific); The production of the second messenge [...] (1265 aa)
     0.920
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide; Guanine nucleotide-binding prote [...] (359 aa)
      0.919
PLCG1
phospholipase C, gamma 1; PLC-gamma is a major substrate for heparin-binding growth factor 1 (a [...] (1291 aa)
     0.918
PLCD1
phospholipase C, delta 1; The production of the second messenger molecules diacylglycerol (DAG) [...] (777 aa)
     0.908
PLCB2
phospholipase C, beta 2; The production of the second messenger molecules diacylglycerol (DAG) [...] (1185 aa)
     0.906
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific); The production of the second messenger mol [...] (1216 aa)
     0.906
PLCB3
phospholipase C, beta 3 (phosphatidylinositol-specific); The production of the second messenger [...] (1234 aa)
     0.906
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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