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  ALX4 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ALX4
ALX homeobox 4; Transcription factor involved in skull and limb development (411 aa)
(Homo sapiens)
Predicted Functional Partners:
GLI3
GLI family zinc finger 3; Plays a role in limb and brain development. Implicated in the transdu [...] (1580 aa)
       0.919
FOXC1
forkhead box C1; Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of th [...] (553 aa)
       0.880
RUNX2
runt-related transcription factor 2; Transcription factor involved in osteoblastic differentiat [...] (589 aa)
       0.878
EXT2
exostoses (multiple) 2; Glycosyltransferase required for the biosynthesis of heparan-sulfate. T [...] (718 aa)
       0.868
SHH
sonic hedgehog homolog (Drosophila); Binds to the patched (PTC) receptor, which functions in as [...] (462 aa)
       0.831
SATB2
SATB homeobox 2; Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to re [...] (733 aa)
       0.829
BMP4
bone morphogenetic protein 4; Induces cartilage and bone formation. Also act in mesoderm induct [...] (408 aa)
       0.798
LEF1
lymphoid enhancer-binding factor 1; Participates in the Wnt signaling pathway. Activates transc [...] (399 aa)
      0.795
HAND2
heart and neural crest derivatives expressed 2; Essential for cardiac morphogenesis, particular [...] (217 aa)
       0.754
ZP2
zona pellucida glycoprotein 2 (sperm receptor); The mammalian zona pellucida, which mediates sp [...] (745 aa)
       0.752
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

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