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  POU3F2 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
POU3F2
POU class 3 homeobox 2; Transcription factor that binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a nonconserved spacer region of 0, 2, or 3 nucleotides. Positively regulates the genes under the control of corticotropin-releasing hormone (CRH) and CRH II promoters (By similarity) (443 aa)
(Homo sapiens)
Predicted Functional Partners:
NES
nestin; May play a role in the trafficking and distribution of IF proteins and potentially othe [...] (1621 aa)
       0.890
NAIP
NLR family, apoptosis inhibitory protein; Prevents motor-neuron apoptosis induced by a variety [...] (1403 aa)
       0.882
PQBP1
polyglutamine binding protein 1; May suppress the ability of POU3F2 to transactivate the DRD1 g [...] (265 aa)
      0.882
LOR
loricrin; Major keratinocyte cell envelope protein (312 aa)
       0.869
SOX10
SRY (sex determining region Y)-box 10; Transcription factor that seems to function synergistica [...] (466 aa)
      0.864
SOX11
SRY (sex determining region Y)-box 11; Probably important in the developing nervous system. May [...] (441 aa)
      0.863
FLG
filaggrin; Aggregates keratin intermediate filaments and promotes disulfide-bond formation amon [...] (4061 aa)
       0.856
IVL
involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia [...] (585 aa)
       0.855
PAX3
paired box 3; Probable transcription factor associated with development of alveolar rhabdomyosa [...] (505 aa)
      0.824
MYT1L
myelin transcription factor 1-like; May function as a panneural transcription factor associated [...] (1184 aa)
       0.794
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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