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  NOS2 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
NOS2
nitric oxide synthase 2, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions (1153 aa)
(Homo sapiens)
Predicted Functional Partners:
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; NF-kappa-B is a pleiotrop [...] (969 aa)
       0.981
TNF
tumor necrosis factor (TNF superfamily, member 2); Cytokine that binds to TNFRSF1A/TNFR1 and TN [...] (233 aa)
       0.978
ARG1
arginase, liver (322 aa)
      0.976
ARG2
arginase, type II; May play a role in the regulation of extra-urea cycle arginine metabolism an [...] (354 aa)
      0.970
IL1B
interleukin 1, beta; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation [...] (269 aa)
       0.970
TLR4
toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to ba [...] (839 aa)
      0.965
MYD88
myeloid differentiation primary response gene (88); Adapter protein involved in the Toll-like r [...] (309 aa)
      0.965
IFNG
interferon, gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamm [...] (166 aa)
       0.961
TLR2
toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial l [...] (784 aa)
      0.954
IRF1
interferon regulatory factor 1; Specifically binds to the upstream regulatory region of type I [...] (325 aa)
       0.953
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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