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  STK11 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
STK11
serine/threonine kinase 11; Essential role in G1 cell cycle arrest. Phosphorylates and activates members of the AMPK-related subfamily of protein kinases. Tumor suppressor (433 aa)
(Homo sapiens)
Predicted Functional Partners:
STRADA
STE20-related kinase adaptor alpha; Pseudokinase which, in complex with CAB39, binds to and act [...] (431 aa)
     0.999
CAB39
calcium binding protein 39; Together with the STE20-related adaptor-alpha (STRAD alpha) pseudo [...] (341 aa)
     0.999
CDC37
microRNA 1181; Co-chaperone that binds to numerous kinases and promotes their interaction with [...] (378 aa)
     0.999
SMAD4
SMAD family member 4; Common mediator of signal transduction by TGF-beta (transforming growth f [...] (552 aa)
      0.993
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member [...] (1679 aa)
      0.987
STK11IP
serine/threonine kinase 11 interacting protein; May regulate STK11 function by controlling its [...] (1099 aa)
     0.984
ETV4
ets variant 4; Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; [...] (484 aa)
      0.984
PTEN
phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatas [...] (403 aa)
      0.982
CAB39L
calcium binding protein 39-like (337 aa)
     0.981
MYC
v-myc myelocytomatosis viral oncogene homolog (avian); Participates in the regulation of gene t [...] (454 aa)
      0.978
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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