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  POLE protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
POLE
polymerase (DNA directed), epsilon; Participates in DNA repair and in chromosomal DNA replication (2286 aa)
(Homo sapiens)
Predicted Functional Partners:
POLE2
polymerase (DNA directed), epsilon 2 (p59 subunit); Participates in DNA repair and in chromosom [...] (527 aa)
    0.999
POLE4
polymerase (DNA-directed), epsilon 4 (p12 subunit); May play a role in allowing polymerase epsi [...] (117 aa)
     0.999
POLE3
polymerase (DNA directed), epsilon 3 (p17 subunit); Forms a complex with DNA polymerase epsilon [...] (147 aa)
    0.999
PCNA
proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delt [...] (261 aa)
    0.997
POLA1
polymerase (DNA directed), alpha 1, catalytic subunit; Plays an essential role in the initiatio [...] (1462 aa)
   0.991
PRIM1
primase, DNA, polypeptide 1 (49kDa); DNA primase is the polymerase that synthesizes small RNA p [...] (420 aa)
     0.955
PRIM2
primase, DNA, polypeptide 2 (58kDa); DNA primase is the polymerase that synthesizes small RNA p [...] (509 aa)
     0.949
CDC45
CDC45 cell division cycle 45-like (S. cerevisiae); Required for initiation of chromosomal DNA r [...] (566 aa)
     0.945
MCM5
minichromosome maintenance complex component 5 (734 aa)
     0.935
MCM3
minichromosome maintenance complex component 3; Acts as a factor that allows the DNA to undergo [...] (808 aa)
     0.934
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
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additional (white) nodes

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