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  MAPK9 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
MAPK9
mitogen-activated protein kinase 9; Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T- cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells (424 aa)
(Homo sapiens)
Predicted Functional Partners:
JUN
jun oncogene; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'- [...] (331 aa)
     0.999
TP53
tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apo [...] (393 aa)
     0.998
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1; The JNK-interacting protein (JIP) gro [...] (711 aa)
      0.989
CDC42
cell division cycle 42 (GTP binding protein, 25kDa); Plasma membrane-associated small GTPase wh [...] (191 aa)
      0.983
DUSP1
dual specificity phosphatase 1; Dual specificity phosphatase that dephosphorylates MAP kinase E [...] (367 aa)
      0.983
BCL2L11
BCL2-like 11 (apoptosis facilitator); Induces apoptosis. Isoform BimL is more potent than isofo [...] (198 aa)
     0.982
RAC1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); Plasma [...] (211 aa)
      0.980
TRAF6
TNF receptor-associated factor 6; Adapter protein and signal transducer that links members of t [...] (522 aa)
      0.979
CD40
CD40 molecule, TNF receptor superfamily member 5; Receptor for TNFSF5/CD40LG (277 aa)
      0.978
NGF
nerve growth factor (beta polypeptide); Nerve growth factor is important for the development an [...] (241 aa)
      0.975
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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