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  GHRHR protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
GHRHR
growth hormone releasing hormone receptor; Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion (423 aa)
(Homo sapiens)
Predicted Functional Partners:
GHRH
growth hormone releasing hormone; GRF is released by the hypothalamus and acts on the adenohypo [...] (108 aa)
     0.999
GNAS
GNAS complex locus; Guanine nucleotide-binding proteins (G proteins) are involved as modulators [...] (1037 aa)
      0.992
SCT
secretin; Stimulates formation of NaHCO(3)-rich pancreatic juice and secretion of NaHCO(3)-rich [...] (121 aa)
      0.974
POU1F1
POU class 1 homeobox 1; Transcription factor involved in the specification of the lactotrope, s [...] (317 aa)
       0.968
GH1
growth hormone 1; Plays an important role in growth control. Its major role in stimulating body [...] (217 aa)
       0.968
PROP1
PROP paired-like homeobox 1; Possibly involved in the ontogenesis of pituitary gonadotropes, as [...] (226 aa)
       0.965
IGHD
immunoglobulin heavy constant delta (430 aa)
       0.964
GCG
glucagon; Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity [...] (180 aa)
      0.958
LHCGR
luteinizing hormone/choriogonadotropin receptor; Receptor for lutropin-choriogonadotropic hormo [...] (699 aa)
      0.953
IGF1
insulin-like growth factor 1 (somatomedin C); The insulin-like growth factors, isolated from pl [...] (195 aa)
       0.947
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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