GBA protein (Homo sapiens) - STRING interaction network

GBA protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	GBA	glucosidase, beta; acid (includes glucosylceramidase) (536 aa)
		(Homo sapiens)
Predicted Functional Partners:
	GALC	galactosylceramidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsph [...] (685 aa)		•	•	0.983
	UGCG	UDP-glucose ceramide glucosyltransferase; Catalyzes the first glycosylation step in glycosphing [...] (394 aa)		•	•	0.978
	GLB1	galactosidase, beta 1; Cleaves beta-linked terminal galactosyl residues from gangliosides, glyc [...] (677 aa)		•	•	0.977
	GBA2	glucosidase, beta (bile acid) 2; Non-lysosomal glucosylceramidase that catalyzes the conversion [...] (927 aa)			•	0.971
	PSAP	prosaposin; The lysosomal degradation of sphingolipids takes place by the sequential action of [...] (524 aa)	•		•	0.962
	CHIT1	chitinase 1 (chitotriosidase); Degrades chitin and chitotriose. May participate in the defense [...] (466 aa)			•	0.956
	ASAH1	N-acylsphingosine amidohydrolase (acid ceramidase) 1; Hydrolyzes the sphingolipid ceramide into [...] (411 aa)		•	•	0.948
	SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal; Converts sphingomyelin to ceramide. Also has [...] (631 aa)		•	•	0.945
	SMPD4	sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3); Catalyzes the [...] (866 aa)		•	•	0.921
	ENPP7	ectonucleotide pyrophosphatase/phosphodiesterase 7; Converts sphingomyelin to ceramide. Also ha [...] (458 aa)		•	•	0.921

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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