version_number_image
  TNKS protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase; May regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Has PARP activity and can modify TERF1, and thereby contribute to the regulation of telomere length (1327 aa)
(Homo sapiens)
Predicted Functional Partners:
TERF1
telomeric repeat binding factor (NIMA-interacting) 1; Binds the telomeric double-stranded TTAGG [...] (439 aa)
      0.999
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa (1729 aa)
      0.987
FNBP1
formin binding protein 1; May act as a link between RND2 signaling and regulation of the actin [...] (617 aa)
      0.987
NUMA1
nuclear mitotic apparatus protein 1; May be a structural component of the nucleus (2115 aa)
      0.959
TINF2
TERF1 (TRF1)-interacting nuclear factor 2; Component of the shelterin complex (telosome) that i [...] (451 aa)
       0.953
POT1
POT1 protection of telomeres 1 homolog (S. pombe); Component of the telomerase ribonucleoprotei [...] (634 aa)
      0.946
TERF2
telomeric repeat binding factor 2; Binds the telomeric double-stranded TTAGGG repeat. Protects [...] (500 aa)
       0.927
KPNB1
karyopherin (importin) beta 1; Functions in nuclear protein import, either in association with [...] (876 aa)
      0.924
POLE
polymerase (DNA directed), epsilon; Participates in DNA repair and in chromosomal DNA replicati [...] (2286 aa)
       0.907
XPO7
exportin 7; Mediates the nuclear export of proteins (cargos) with broad substrate specificity. [...] (1096 aa)
       0.899
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (2%)
Permalink