TNKS protein (Homo sapiens) - STRING interaction network

TNKS protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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	TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase; May regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Has PARP activity and can modify TERF1, and thereby contribute to the regulation of telomere length (1327 aa)
		(Homo sapiens)
Predicted Functional Partners:
	TERF1	telomeric repeat binding factor (NIMA-interacting) 1; Binds the telomeric double-stranded TTAGG [...] (439 aa)	•		•	0.999
	TNKS1BP1	tankyrase 1 binding protein 1, 182kDa (1729 aa)	•		•	0.987
	FNBP1	formin binding protein 1; May act as a link between RND2 signaling and regulation of the actin [...] (617 aa)	•		•	0.987
	NUMA1	nuclear mitotic apparatus protein 1; May be a structural component of the nucleus (2115 aa)	•		•	0.959
	TINF2	TERF1 (TRF1)-interacting nuclear factor 2; Component of the shelterin complex (telosome) that i [...] (451 aa)			•	0.953
	POT1	POT1 protection of telomeres 1 homolog (S. pombe); Component of the telomerase ribonucleoprotei [...] (634 aa)	•		•	0.946
	TERF2	telomeric repeat binding factor 2; Binds the telomeric double-stranded TTAGGG repeat. Protects [...] (500 aa)			•	0.927
	KPNB1	karyopherin (importin) beta 1; Functions in nuclear protein import, either in association with [...] (876 aa)		•	•	0.924
	POLE	polymerase (DNA directed), epsilon; Participates in DNA repair and in chromosomal DNA replicati [...] (2286 aa)			•	0.907
	XPO7	exportin 7; Mediates the nuclear export of proteins (cargos) with broad substrate specificity. [...] (1096 aa)		•		0.899

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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