TERT protein (Homo sapiens) - STRING interaction network

TERT protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	TERT	telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme (1132 aa)
		(Homo sapiens)
Predicted Functional Partners:
	AKT1	v-akt murine thymoma viral oncogene homolog 1; General protein kinase capable of phosphorylatin [...] (480 aa)	•	•	•	0.999
	DKC1	small nucleolar RNA, H/ACA box 56; Required for ribosome biogenesis and telomere maintenance. P [...] (514 aa)	•	•	•	0.998
	WRAP53	WD repeat containing, antisense to TP53; Essential component of the telomerase holoenzyme compl [...] (548 aa)		•	•	0.997
	SP1	Sp1 transcription factor; Transcription factor that can activate or repress transcription in re [...] (785 aa)		•	•	0.995
	MYC	v-myc myelocytomatosis viral oncogene homolog (avian); Participates in the regulation of gene t [...] (454 aa)		•	•	0.995
	RUVBL1	RuvB-like 1 (E. coli); Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA h [...] (456 aa)	•	•	•	0.995
	RUVBL2	RuvB-like 2 (E. coli); Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA h [...] (463 aa)	•	•	•	0.995
	SMG6	Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans); Component of the telomerase ri [...] (1419 aa)	•	•	•	0.991
	ABL1	c-abl oncogene 1, receptor tyrosine kinase; Regulates cytoskeleton remodeling during cell diffe [...] (1149 aa)	•	•	•	0.991
	XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6; Single stranded DNA-dep [...] (609 aa)	•	•	•	0.986

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes

Server load: low (37%)

Permalink